Jane Osbourn

Human Antibodies with Sub-nanomolar Affinities Isolated from a Large Non-immunized Phage Display Library

Tristan J. Vaughan, Andrew J Williams, Kevin Pritchard et al. · Nature Biotechnology · 1996 · 1K citations

Immunocytochemical Technique, Biomedical Diagnostics, Natural Sciences +11

A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy

John Y. Li, Samuel R. Perry, Vanessa Muniz‐Medina et al. · Cancer Cell · 2016 · 375 citations · Full text

Drug Targeting, Her2-targeted Therapy, Medicine +10

A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

Michael D. Miller, Romas Geleziunas, Elisabetta Bianchi et al. · Proceedings of the National Academy of Sciences · 2005 · 155 citations · Full text

Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures

Jacob D. Galson, Sebastian Schaetzle, Rachael Bashford-Rogers et al. · Frontiers in Immunology · 2020 · 150 citations · Full text

Vaccination, Adaptive Immune System, Vaccine Target +13

From rodent reagents to human therapeutics using antibody guided selection

Jane Osbourn, Maria Groves, Tristan J. Vaughan · Methods · 2005 · 94 citations

Xenotransplantation, Medicine, Immunology +8