Concepedia

Alternative Cleavage

Alternative Cleavage is a post-transcriptional regulatory mechanism in molecular biology wherein a single pre-mRNA transcript undergoes cleavage at multiple potential polyadenylation sites, leading to the generation of mRNA isoforms with differing 3′ untranslated regions or coding sequences.

92

Publications

8.4K

Citations

431

Authors

171

Institutions

Publications per year

2017–2026

25

Variants

Apa

Parents

Publications

92

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

Christine Mayr, David P. Bartel · Cell · 2009 · 991 citations · Full text

, , +17

Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing

Mainul Hoque, Zhe Ji, Dinghai Zheng et al. · Nature Methods · 2012 · 462 citations · Full text

, , +16

Most “Dark Matter” Transcripts Are Associated With Known Genes

Harm van Bakel, Corey Nislow, Benjamin J. Blencowe et al. · PLoS Biology · 2010 · 434 citations · Full text

, , +14

Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

Steve Lianoglou, Vidur Garg, Julie L. Yang et al. · Genes & Development · 2013 · 417 citations · Full text

, , +17

Widespread and extensive lengthening of 3′ UTRs in the mammalian brain

Pedro Miura, Sol Shenker, Celia Andreu-Agulló et al. · Genome Research · 2013 · 373 citations · Full text

, , +15

1–5 of 92

Authors

431

  1. BT
    Bin Tian

    Rutgers, The State University of New Jersey, United States

    13 publications · 1.7K citations

    13

    h-index

  2. DZ
    Dinghai Zheng

    Rutgers, The State University of New Jersey, United States

    8 publications · 1.3K citations

    8

    h-index

  3. MH
    Mainul Hoque

    Rutgers, The State University of New Jersey, United States

    7 publications · 1.2K citations

    7

    h-index

  4. WL
    Wencheng Li

    Rutgers New Jersey Medical School, United States

    6 publications · 1.1K citations

    6

    h-index

  5. RE
    Ran Elkon

    Tel Aviv University, Israel

    5 publications · 709 citations

    5

    h-index

1–5 of 431

Institutions

171

  1. Rutgers, The State University of New Jersey

    New Brunswick, United States

    13 h-index

    61 publications

    10.5K citations

  2. Rutgers New Jersey Medical School

    Newark, United States

    12 h-index

    54 publications

    9.6K citations

  3. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    5 h-index

    48 publications

    6.3K citations

  4. Rutgers Cancer Institute

    New Brunswick, United States

    4 h-index

    8 publications

    1.4K citations

  5. Kettering University

    Flint, United States

    3 h-index

    14 publications

    3.3K citations

  6. University of Oxford

    Oxford, United Kingdom

    3 h-index

    16 publications

    2K citations

  7. Oncode Institute

    Utrecht, Netherlands

    3 h-index

    25 publications

    4.5K citations

  8. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    5 publications

    200 citations

1–8 of 171

Venues

  1. Journal of Biological Chemistry

    JBC · 8 publications · 481 citations

    8

    h-index

  2. Nucleic Acids Research

    5 publications · 339 citations

    5

    h-index

  3. RNA

    4 publications · 264 citations

    4

    h-index

  4. PLoS Genetics

    3 publications · 453 citations

    3

    h-index

  5. Biochemistry

    3 publications · 133 citations

    3

    h-index

1–5