Concepedia

Allosteric Stabilization

Allosteric Stabilization is a biochemical mechanism in which the binding of a ligand at an allosteric site distinct from the enzyme's active site induces a conformational change that enhances the structural stability and functional integrity of the enzyme.

93

Publications

4.9K

Citations

426

Authors

150

Institutions

Publications per year

2017–2026

13

Parents

Publications

93

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

Vivian Barry-Hamilton, Rhyannon Spangler, Derek Marshall et al. · Nature Medicine · 2010 · 855 citations

, , +13

An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme

Derek F. Ceccarelli, Xiaojing Tang, Benoit Pelletier et al. · Cell · 2011 · 234 citations · Full text

, , +12

An allosteric mechanism for potent inhibition of human ATP-citrate lyase

Wei Jia, Silvana Leit, Jun Kuai et al. · Nature · 2019 · 192 citations

, , +13

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization

J.W. Fairman, Sanath R. Wijerathna, Shabbir Ahmad et al. · Nature Structural & Molecular Biology · 2011 · 176 citations · Full text

, , +16

A common allosteric site and mechanism in caspases

Justin M. Scheer, M.J. Romanowski, James A. Wells · Proceedings of the National Academy of Sciences · 2006 · 169 citations · Full text

, , +17

1–5 of 93

Authors

426

  1. GH
    Gerhard H. Braus

    University of Göttingen, Germany

    4 publications · 162 citations

    4

    h-index

  2. ML
    Mario L. Calcagno

    Universidad Nacional Autónoma de México, Mexico

    3 publications · 71 citations

    3

    h-index

  3. NB
    Neil B. Madsen

    University of Alberta, Canada

    3 publications · 232 citations

    3

    h-index

  4. WN
    William N. Lipscomb

    Harvard University, United States

    3 publications · 147 citations

    3

    h-index

  5. EH
    E. Horjales

    Universidad Nacional Autónoma de México, Mexico

    2 publications · 57 citations

    2

    h-index

1–5 of 426

Institutions

150

  1. Harvard University

    Cambridge, United States

    5 h-index

    12 publications

    722 citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    18 publications

    473 citations

  3. University of Alberta

    Edmonton, Canada

    3 h-index

    5 publications

    381 citations

  4. University of Göttingen

    Göttingen, Germany

    3 h-index

    9 publications

    355 citations

  5. Case Western Reserve University

    Cleveland, United States

    3 h-index

    15 publications

    1.8K citations

  6. Universidad Nacional Autónoma de México

    Mexico City, Mexico

    3 h-index

    11 publications

    255 citations

  7. Yale University

    New Haven, United States

    3 h-index

    11 publications

    615 citations

  8. University of Michigan

    Ann Arbor, United States

    3 h-index

    6 publications

    286 citations

1–8 of 150

Venues

  1. Journal of Biological Chemistry

    JBC · 12 publications · 494 citations

    12

    h-index

  2. Journal of Molecular Biology

    JMB · 12 publications · 531 citations

    12

    h-index

  3. Biochemistry

    5 publications · 211 citations

    5

    h-index

  4. Structure

    5 publications · 287 citations

    5

    h-index

  5. Archives of Biochemistry and Biophysics

    ABB · 4 publications · 89 citations

    4

    h-index

1–5