Concepedia

Admet Optimization

ADMET Optimization is a drug discovery process that systematically enhances a compound's absorption, distribution, metabolism, excretion, and toxicity properties to improve its pharmacokinetic and safety profile while maintaining desired biological activity.

312

Publications

16.8K

Citations

1.6K

Authors

590

Institutions

Publications per year

2017–2026

256

Parents

Publications

312

ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties

Guo‐Li Xiong, Jiacai Yi, Li Fu et al. · Nucleic Acids Research · 2021 · 2.7K citations · Full text

, , +16

admetSAR 2.0: web-service for prediction and optimization of chemical ADMET properties

Hongbin Yang, Chaofeng Lou, Lixia Sun et al. · Bioinformatics · 2018 · 1.4K citations

, , +16

ADMET-score – a comprehensive scoring function for evaluation of chemical drug-likeness

Longfei Guan, Hongbin Yang, Yingchun Cai et al. · MedChemComm · 2018 · 694 citations

, , +16

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

Philip A. Harris, Scott B. Berger, Jae Uk Jeong et al. · Journal of Medicinal Chemistry · 2017 · 475 citations · Full text

, , +15

ADMET—turning chemicals into drugs

John Hodgson · Nature Biotechnology · 2001 · 427 citations

, , +11

1–5 of 312

Authors

1.6K

  1. MB
    Mohammed Bouachrıne

    Université Moulay Ismail de Meknes, Morocco

    12 publications · 318 citations

    12

    h-index

  2. TL
    Tahar Lakhlifi

    Université Moulay Ismail de Meknes, Morocco

    10 publications · 283 citations

    10

    h-index

  3. SC
    Samir Chtita

    University of Hassan II Casablanca, Morocco

    8 publications · 272 citations

    8

    h-index

  4. MA
    Marwa Alaqarbeh

    Université Moulay Ismail de Meknes, Morocco

    7 publications · 214 citations

    7

    h-index

  5. ND
    Normi D. Gajjar

    B.J. Medical College, India

    6 publications · 233 citations

    6

    h-index

1–5 of 1.6K

Institutions

590

  1. Sidi Mohamed Ben Abdellah University

    Fes, Morocco

    14 h-index

    57 publications

    1.5K citations

  2. Université Moulay Ismail de Meknes

    Meknes, Morocco

    13 h-index

    66 publications

    1.7K citations

  3. King Saud University

    Riyadh, Saudi Arabia

    13 h-index

    18 publications

    662 citations

  4. University of Chittagong

    Chittagong, Bangladesh

    11 h-index

    43 publications

    1.3K citations

  5. University of Hassan II Casablanca

    Casablanca, Morocco

    10 h-index

    25 publications

    879 citations

  6. National Institute of Pharmaceutical Education and Research

    Mohali, India

    7 h-index

    31 publications

    657 citations

  7. National Research Centre

    Giza, Egypt

    6 h-index

    10 publications

    288 citations

  8. Airlangga University

    Surabaya, Indonesia

    6 h-index

    17 publications

    473 citations

1–8 of 590

Venues

  1. Journal of Molecular Structure

    23 publications · 737 citations

    18

    h-index

  2. Journal of Biomolecular Structure and Dynamics

    19 publications · 570 citations

    15

    h-index

  3. Molecules

    12 publications · 372 citations

    11

    h-index

  4. Journal of Medicinal Chemistry

    7 publications · 739 citations

    7

    h-index

  5. Computational Biology and Chemistry

    CBAC · 7 publications · 174 citations

    7

    h-index

1–5