Concepedia

Active Zone Dysfunction

Active Zone Dysfunction is a pathological alteration in the presynaptic specialization responsible for neurotransmitter release, characterized by impairments in the spatial organization, molecular composition, or functional efficacy of synaptic vesicle exocytosis sites within the active zone.

41

Publications

3.1K

Citations

311

Authors

113

Institutions

Publications per year

2017–2026

10

Parents

Publications

41

Maturation of active zone assembly by <i>Drosophila</i> Bruchpilot

Wernher Fouquet, David Owald, Carolin Wichmann et al. · The Journal of Cell Biology · 2009 · 439 citations · Full text

, , +15

<i>Caenorhabditis elegans rab-3</i>Mutant Synapses Exhibit Impaired Function and Are Partially Depleted of Vesicles

Michael L. Nonet, Jane Staunton, Michael P. Kilgard et al. · Journal of Neuroscience · 1997 · 379 citations · Full text

, , +17

Functional Inactivation of a Fraction of Excitatory Synapses in Mice Deficient for the Active Zone Protein Bassoon

Wilko D. Altrock, Susanne tom Dieck, Maxim Sokolov et al. · Neuron · 2003 · 265 citations · Full text

, , +15

Paucity and disorganization of presynaptic membrane active zones in the lambert‐eaton myasthenic syndrome

Hidetoshi Fukunaga, Andrew G. Engel, Mitsuhiro Osame et al. · Muscle & Nerve · 1982 · 183 citations

, , +16

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

Shan Shan H. Wang, Richard G. Held, Man Yan Wong et al. · Neuron · 2016 · 150 citations · Full text

, , +16

1–5 of 41

Authors

311

  1. JH
    Johann Helmut Brandstätter

    Max Planck Institute for Brain Research, Germany

    3 publications · 446 citations

    3

    h-index

  2. TM
    Tobias M. Rasse

    Hertie Institute for Clinical Brain Research, Germany

    3 publications · 86 citations

    3

    h-index

  3. ST
    Susanne tom Dieck

    Max Planck Institute for Brain Research, Germany

    2 publications · 364 citations

    2

    h-index

  4. JV
    Jeannine V. Kern

    University of Tübingen, Germany

    2 publications · 50 citations

    2

    h-index

  5. TR
    Thomas R. Jahn

    Heidelberg University, Germany

    2 publications · 50 citations

    2

    h-index

1–5 of 311

Institutions

113

  1. University of Tübingen

    Tübingen, Germany

    4 h-index

    25 publications

    1.6K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    8 publications

    1.1K citations

  3. Heidelberg University

    Heidelberg, Germany

    3 h-index

    9 publications

    223 citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    4 publications

    808 citations

  5. Hertie Institute for Clinical Brain Research

    Tübingen, Germany

    3 h-index

    11 publications

    295 citations

  6. Stanford University

    Stanford, United States

    3 h-index

    4 publications

    520 citations

  7. Leibniz Institute for Neurobiology

    Magdeburg, Germany

    2 h-index

    13 publications

    3.1K citations

  8. Friedrich-Alexander-Universität Erlangen-Nürnberg

    Erlangen, Germany

    2 h-index

    8 publications

    690 citations

1–8 of 113

Venues

  1. Journal of Neuroscience

    7 publications · 752 citations

    7

    h-index

  2. Human Molecular Genetics

    3 publications · 201 citations

    3

    h-index

  3. Cell Reports

    2 publications · 56 citations

    2

    h-index

  4. The Journal of Comparative Neurology

    2 publications · 107 citations

    2

    h-index

  5. Neuron

    2 publications · 415 citations

    2

    h-index

1–5