Thomas R. Jahn

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate

Thomas R. Jahn, Martin J. Parker, Steve W. Homans et al. · Nature Structural & Molecular Biology · 2006 · 307 citations · Full text

Alzheimer's Disease, Protein Assembly, Protein Folding +9

The Common Architecture of Cross-β Amyloid

Thomas R. Jahn, O. Sumner Makin, Kyle L. Morris et al. · Journal of Molecular Biology · 2009 · 300 citations

Neurodegenerative Diseases, Molecular Neuroscience, Protein Folding +6

Unconventional Secretion Mediates the Trans-cellular Spreading of Tau

Marcel Zeitler, Eleni Dimou, Andromachi Karakatsani et al. · Cell Reports · 2018 · 264 citations · Full text

Protein Secretion, Molecular Biology, Cytoskeleton +21

Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

Eliana Nachman, Anne S. Wentink, Karine Madiona et al. · Journal of Biological Chemistry · 2020 · 161 citations · Full text

Direct Observation of Oligomeric Species formed in the Early Stages of Amyloid Fibril Formation using Electrospray Ionisation Mass Spectrometry

Andrew M. Smith, Thomas R. Jahn, Alison E. Ashcroft et al. · Journal of Molecular Biology · 2006 · 147 citations · Full text

Oligomeric Species, Biochemistry, Mass Spectrometry +7