Concepedia

Active Site Recognition

Active Site Recognition is a computational method that identifies the specific region within an enzyme where substrate binding and catalysis occur, distinguished by its focus on predicting the precise location and conformation responsible for enzymatic specificity.

247

Publications

14.5K

Citations

1.1K

Authors

364

Institutions

Publications per year

2017–2026

25

Parents

Publications

247

Direct Thrombin Inhibitors

Marcello Di Nisio, Saskia Middeldorp, Harry R. Büller · New England Journal of Medicine · 2005 · 652 citations · Full text

, , +17

Genetic Regulation: The Lac Control Region

Robert C. Dickson, John Abelson, Wayne M. Barnes et al. · Science · 1975 · 519 citations

, , +17

Expanding the Range of Substrate Acceptance of Enzymes: Combinatorial Active‐Site Saturation Test

Manfred T. Reetz, Marco Bocola, José Daniel Carballeira et al. · Angewandte Chemie International Edition · 2005 · 504 citations

, , +14

A conserved 3′→5′ exonuclease active site in prokaryotic and eukaryotic DNA polymerases

António Bernad, Luis Blanco, JoséM. Lázaro et al. · Cell · 1989 · 437 citations

, , +12

Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme

Kiira Ratia, Kumar Singh Saikatendu, Bernard D. Santarsiero et al. · Proceedings of the National Academy of Sciences · 2006 · 434 citations · Full text

, , +17

1–5 of 247

Authors

1.1K

  1. SE
    Stephen E. Halford

    University of Bristol, United Kingdom

    4 publications · 93 citations

    4

    h-index

  2. JP
    Jean‐Philip Piquemal

    Laboratoire de Chimie Théorique, France

    4 publications · 57 citations

    4

    h-index

  3. NG
    Nohad Gresh

    Centre National de la Recherche Scientifique, France

    4 publications · 57 citations

    4

    h-index

  4. AR
    Aharon Razin

    Hebrew University of Jerusalem, Israel

    2 publications · 27 citations

    2

    h-index

  5. BA
    Bernard A. Connolly

    Newcastle University, United Kingdom

    2 publications · 67 citations

    2

    h-index

1–5 of 1.1K

Institutions

364

  1. National Institutes of Health

    Bethesda, United States

    7 h-index

    15 publications

    1.4K citations

  2. Johns Hopkins University

    Baltimore, United States

    6 h-index

    12 publications

    546 citations

  3. University of Bristol

    Bristol, United Kingdom

    5 h-index

    13 publications

    314 citations

  4. Harvard University

    Cambridge, United States

    5 h-index

    13 publications

    793 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    18 publications

    345 citations

  6. Iowa State University

    Ames, United States

    5 h-index

    12 publications

    324 citations

  7. Yale University

    New Haven, United States

    5 h-index

    12 publications

    1.5K citations

  8. Université Paris Cité

    Paris, France

    4 h-index

    13 publications

    423 citations

1–8 of 364

Venues

  1. Journal of Biological Chemistry

    JBC · 32 publications · 1.7K citations

    22

    h-index

  2. Biochemistry

    19 publications · 1.1K citations

    17

    h-index

  3. Nucleic Acids Research

    19 publications · 598 citations

    15

    h-index

  4. Journal of Molecular Biology

    JMB · 11 publications · 946 citations

    11

    h-index

  5. Journal of the American Chemical Society

    JACS · 8 publications · 353 citations

    8

    h-index

1–5