Manfred T. Reetz

Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes

Manfred T. Reetz, José Daniel Carballeira · Nature Protocols · 2007 · 845 citations

Functional Enzymes, Engineering, Natural Sciences +11

Combinatorial and Evolution-Based Methods in the Creation of Enantioselective Catalysts

Manfred T. Reetz · Angewandte Chemie International Edition · 2001 · 588 citations

Bioorganic Chemistry, Engineering, Organic Chemistry +16

Expanding the Range of Substrate Acceptance of Enzymes: Combinatorial Active‐Site Saturation Test

Manfred T. Reetz, Marco Bocola, José Daniel Carballeira et al. · Angewandte Chemie International Edition · 2005 · 498 citations

Engineering, Amino Acids, Biochemistry +15

Iterative Saturation Mutagenesis on the Basis of B Factors as a Strategy for Increasing Protein Thermostability

Manfred T. Reetz, José Daniel Carballeira, Andreas Vogel · Angewandte Chemie International Edition · 2006 · 473 citations

Engineering, Molecular Biology, B Factors +18

Addressing the Numbers Problem in Directed Evolution

Manfred T. Reetz, Daniel Kahakeaw, Renate Lohmer · ChemBioChem · 2008 · 435 citations