Genetic Epidemiology

Genetic epidemiology is the study of the role of genetic factors and their environmental interactions in the etiology, distribution, and control of disease in families and populations.

29.7K

Publications

1.8M

Citations

122.9K

Authors

12.3K

Institutions

Publications per year

2017–2026

6.4K

Parents

Genetics

Children

Candidate Gene StudiesCausal Inference In GeneticsComplex Trait GeneticsDisease Susceptibility LociEpigenetic EpidemiologyFamilial AggregationGene-environment InteractionGenetic Risk FactorsGenetic Risk PredictionGenome-wide Association Studies

Publications

29.7K

Fast model-based estimation of ancestry in unrelated individuals

David H. Alexander, John Novembre, Kenneth Lange · Genome Research · 2009 · 10.6K citations · Full text

Public Health, Biostatistics, Genetics +14

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

Jack Bowden, George Davey Smith, Stephen Burgess · International Journal of Epidemiology · 2015 · 10.6K citations · Full text

Public Health, Biostatistics, Genetics +15

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Panos Deloukas, Audrey Duncanson, Dominic Kwiatkowski et al. · Nature · 2007 · 9.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

Jack Bowden, George Davey Smith, Philip Haycock et al. · Genetic Epidemiology · 2016 · 9.6K citations · Full text

Life Sciences, Biostatistics, Genetics +12

Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene

Avshalom Caspi, Karen Sugden, Terrie E. Moffitt et al. · Science · 2003 · 8.1K citations

Life Sciences, Genetics, Molecular Genetics +17

1–5 of 29.7K

Authors

122.9K

GD
George Davey Smith
University of Bristol, United Kingdom
205 publications · 62.9K citations
90
h-index
CM
Cornelia M. van Duijn
Erasmus MC, Netherlands
167 publications · 21.6K citations
70
h-index
NG
Nicholas G. Martin
QIMR Berghofer Medical Research Institute, Australia
168 publications · 18.7K citations
69
h-index
EB
Eric Boerwinkle
The University of Texas Health Science Center at Houston, United States
207 publications · 25.3K citations
69
h-index
SJ
Stephen J. Chanock
National Cancer Institute, United States
166 publications · 17.9K citations
68
h-index

1–5 of 122.9K

Institutions

12.3K

1–8 of 12.3K

Venues

The American Journal of Human Genetics
AJHG · 224 publications · 45.6K citations
111
h-index
PubMed
Repository · 1.8K publications · 75.6K citations
111
h-index
Nature Genetics
118 publications · 74.9K citations
105
h-index
Diabetes
307 publications · 31K citations
102
h-index
Genetic Epidemiology
652 publications · 52.3K citations
96
h-index

1–5

See also Genetic Epidemiology
Core Methods	Genome-wide Association Studies Linkage Analysis Twin Studies Multipoint Linkage Analysis Transmission Disequilibrium Test Family-based Association Tests Genetic Relationship Matrix
Gene Environment Interaction	Gene-environment Interaction Exposure Assessment Epigenetic Alterations Varying-coefficient Models Metabolism Enzyme Polymorphisms
Applications	Heritability Disease Control Mendelian Disorders Population Genomic Screening Health Economics Of Pharmacogenomics Disease Spread Surveillance Chronic Disease Incidence Estimation
Limitations	Population Stratification Missing Heritability Horizontal Pleiotropy Weak Instrument Bias Rare Variant Stratification