Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation

Melissa Holtz, Marilyn L. Slovak, Feiyu Zhang, +3

Blood

The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD⁺) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

Xun Zhao, Dagart Allison, Bradley Condon, +9

Journal of Medicinal Chemistry

Crystal StructureAldo-keto ReductaseMolecular RegulationMolecular BiologyEpigenetics +18

Human T Lymphocyte Genetic Modification with Naked DNA

Michael C. Jensen, Patrick Clarke, Giselle Tan, +8

Molecular Therapy

Structural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET Domain

Stephen Antonysamy, Bradley Condon, Zhanna Druzina, +9

PLoS ONE

Histone ModificationsCrystal StructureEpigenetic ChangeMolecular BiologyNovel Crystal Structure +21

Sarcopenia: a new predictor of postoperative complications for elderly gastric cancer patients who underwent radical gastrectomy

Chong-Jun Zhou, Feng‐Min Zhang, Feiyu Zhang, +2

Journal of Surgical Research

Surgical OncologyUnderwent Radical GastrectomyGastrointestinal OncologyNew PredictorGastroenterology +5

Efficient Delivery of GSDMD‐N mRNA by Engineered Extracellular Vesicles Induces Pyroptosis for Enhanced Immunotherapy

Yuqi Xing, Feiyu Zhang, Panpan Ji, +5

Small

Novel lactylation-related signature to predict prognosis for pancreatic adenocarcinoma

Peng Tian, Fang Sun, Jia-Chun Yang, +5

World Journal of Gastroenterology

Role of frailty and nutritional status in predicting complications following total gastrectomy with D2 lymphadenectomy in patients with gastric cancer: a prospective study

Fan‐Feng Chen, Feiyu Zhang, Xuan-You Zhou, +3

Langenbeck s Archives of Surgery

ObesityBariatric SurgeryGastrointestinal OncologyTotal GastrectomyMedicine +5

Chronic myelogenous leukemia primitive hematopoietic progenitors demonstrate increased sensitivity to growth factor–induced proliferation and maturation

Ravi Bhatia, Heidi A. Munthe, Andrea D Williams, +3

Experimental Hematology

Hematological MalignancyDevelopmental BiologyImmune Cell DevelopmentMedicineHematology +9

Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China

Yujie Ning, Minhan Hu, Yi Gong, +13

Arthritis Research & Therapy