Joe A. Tran

Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor

Mustapha Haddach, Jerome Michaux, Michael K. Schwaebe et al. · ACS Medicinal Chemistry Letters · 2011 · 86 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Practical Asymmetric Synthesis of α-Branched 2-Piperazinylbenzylamines by 1,2-Additions of Organometallic Reagents to <i>N</i>-<i>tert</i>-Butanesulfinyl Imines

Wanlong Jiang, Chen Chen, Dragan Marinkovic et al. · The Journal of Organic Chemistry · 2005 · 37 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Studies on the structure–activity relationship of bicifadine analogs as monoamine transporter inhibitors

Mingzhu Zhang, Florence Jovic, Troy Vickers et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 32 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines

Fábio C. Tucci, Nicole S. White, Stacy Markison et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 32 citations

Medicine, Medicinal Chemistry, Pharmacology +14

4-{(<i>2R</i>)-[3-Aminopropionylamido]-3-(2,4-dichlorophenyl)propionyl}-1-{2-[(2-thienyl)ethylaminomethyl]phenyl}piperazine as a Potent and Selective Melanocortin-4 Receptor AntagonistDesign, Synthesis, and Characterization

Chen Chen, Joseph Pontillo, Beth A. Fleck et al. · Journal of Medicinal Chemistry · 2004 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15