Kati J. Ahlqvist

Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance

Gavin Hudson, Patrizia Amati‐Bonneau, Emma L. Blakely et al. · Brain · 2007 · 421 citations · Full text

Life Sciences, Genetics, Ophthalmology +17

Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice

Kati J. Ahlqvist, Riikka H. Hämäläinen, Shuichi Yatsuga et al. · Cell Metabolism · 2012 · 240 citations · Full text

Life Sciences, Genetics, Molecular Genetics +8

Metabolic determination of cell fate through selective inheritance of mitochondria

Julia Döhla, Emilia Kuuluvainen, Nadja Gebert et al. · Nature Cell Biology · 2022 · 95 citations · Full text

Life Sciences, Cell Biology, Genetics +10

Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias

Riikka H. Hämäläinen, Juan C. Landoni, Kati J. Ahlqvist et al. · Nature Metabolism · 2019 · 85 citations

Life Sciences, Biology, Genetics +16

mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling

Riikka H. Hämäläinen, Kati J. Ahlqvist, Pekka Ellonen et al. · Cell Reports · 2015 · 80 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17