Concepedia

Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias

Riikka H. Hämäläinen, Juan C. Landoni, Kati J. Ahlqvist, Steffi Goffart, Sanna Ryytty, M. Obaidur Rahman, Virginia Brilhante, Katherine Icay, Sampsa Hautaniemi, Liya Wang,

Nature Metabolism · 2019 · 81 citations · 32 references

DOI

Concepts

References

32

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin, Carrie Davis, Felix Schlesinger et al. · Bioinformatics · 2012 · 53.2K citations · Full text

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Cole Trapnell, Adam Roberts, Loyal A. Goff et al. · Nature Protocols · 2012 · 12.6K citations · Full text

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E. Carpenter, Thouis R. Jones, Michael R. Lamprecht et al. · Genome biology · 2006 · 5.4K citations · Full text

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature · 2004 · 2.7K citations

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Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

Gregory C. Kujoth, Asimina Hiona, Thomas D. Pugh et al. · Science · 2005 · 2.1K citations

, , +12