Virginia Brilhante

Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy

Eija Pirinen, Mari Auranen, Nahid Khan et al. · Cell Metabolism · 2020 · 294 citations · Full text

Life Sciences, Biochemistry, Physiology +16

Genetic Basis of Severe Childhood-Onset Cardiomyopathies

Catalina Vasilescu, Tiina Ojala, Virginia Brilhante et al. · Journal of the American College of Cardiology · 2018 · 161 citations

Medicine, Genetics, Molecular Genetics +14

Whole-exome sequencing identifies a mutation in the mitochondrial ribosome protein MRPL44 to underlie mitochondrial infantile cardiomyopathy

Christopher J. Carroll, Pirjo Isohanni, Rosanna Pöyhönen et al. · Journal of Medical Genetics · 2013 · 102 citations

Life Sciences, Genetics, Molecular Genetics +17

Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias

Riikka H. Hämäläinen, Juan C. Landoni, Kati J. Ahlqvist et al. · Nature Metabolism · 2019 · 85 citations

Life Sciences, Biology, Genetics +16

Mitochondrial EFTs defects in juvenile-onset Leigh disease, ataxia, neuropathy, and optic atrophy

Sofia Ahola, Pirjo Isohanni, Liliya Euro et al. · Neurology · 2014 · 37 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17