K858, a Novel Inhibitor of Mitotic Kinesin Eg5 and Antitumor Agent, Induces Cell Death in Cancer Cells

Ryuichiro Nakai, Shin-ichi Iida, Takeshi Takahashi, +13

Cancer Research

UCS1025A and B, New Antitumor Antibiotics from the Fungus <i>Acremonium</i> Species

Tsutomu Agatsuma, Tsutomu Akama, Shinji Nara, +7

Organic Letters

New Antitumor AntibioticsMedicinal FungiOrganic ChemistryAntimicrobial ChemotherapyHeterocycle Chemistry +18

Thermophilic Alkaline Xylanase from Newly Isolated Alkaliphilic and Thermophilic<i>Bacillus</i>sp. Strain TAR-1

Satoshi Nakamura, Ryuichiro Nakai, Kenji Wakabayashi, +3

Bioscience Biotechnology and Biochemistry

BiosynthesisBiomanufacturingEngineeringBiochemistryBiotransformation +11

UCS1025A, a Novel Antibiotic Produced by Acremonium sp.

Ryuichiro Nakai, Harumi Ogawa, Akira Asai, +6

The Journal of Antibiotics

MPC1001 and Its Analogues:  New Antitumor Agents from the Fungus <i>Cladorrhinum</i> Species

Hideyuki Onodera, Atsuhiro Hasegawa, Noriko Tsumagari, +3

Organic Letters

The Discovery and Characterization of K-756, a Novel Wnt/β-Catenin Pathway Inhibitor Targeting Tankyrase

Ryoko Okada-Iwasaki, Yuichi Takahashi, Yasuo Watanabe, +4

Molecular Cancer Therapeutics

Telomerase Inhibitors Identified by a Forward Chemical Genetics Approach Using a Yeast Strain with Shortened Telomere Length

Ryuichiro Nakai, Hiroyuki Ishida, Akira Asai, +6

Chemistry & Biology

Genome InstabilityNatural SciencesGeneticsShortened Telomere LengthMolecular Biology +9

An anti-ASCT2 monoclonal antibody suppresses gastric cancer growth by inducing oxidative stress and antibody dependent cellular toxicity in preclinical models.

Aya Osanai-Sasakawa, Kenta Hosomi, Yoshiki Sumitomo, +11

PubMed

ImmunologyCancer BiologyTumor BiologyOxidative StressOncology +15

A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer Cells and Shows Potent Antitumor Activity in Xenograft Tumor Models

Xiang S. Ye, Fan Li, Robert D. Van Horn, +13

Molecular Cancer Therapeutics

ApoptosisCell DeathCancer BiologyTumor BiologyAnti-cancer Agent +15

MPC1001, a New Antitumor Antibiotic Produced by Cladorrhinum sp.

Noriko Tsumagari, Ryuichiro Nakai, Hideyuki Onodera, +4

The Journal of Antibiotics

Antimicrobial Drug DiscoveryAntibioticsPharmacotherapyAntibacterial AgentMicrobiology +5