Yasushi Tomii

Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity

Nobuya Ishii, Naoki Harada, Eric W. Joseph et al. · Cancer Research · 2013 · 160 citations

Raf Feedback Limits, Raf Activity, Cancer Biology +17

Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment

Futa Mimoto, K. Tatsumi, Shun Shimizu et al. · Cell Reports · 2020 · 62 citations · Full text

Cancer Immunosurveillance, Elevated Extracellular Atp, Medicine +15

Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical Properties

Ikumi Hyohdoh, Noriyuki Furuichi, Toshihiro Aoki et al. · ACS Medicinal Chemistry Letters · 2013 · 36 citations · Full text

Engineering, Chemical Analysis, Lead Identification +23

Cell binding isoforms of vascular endothelial growth factor-A (VEGF189) contribute to blood flow-distant metastasis of pulmonary adenocarcinoma

Masatake Nishi, Yoshiyuki Abe, Yasushi Tomii et al. · International Journal of Oncology · 2005 · 34 citations

Increased Vegf189 Expression, Pathology, Tumor Biology +20

Interleukin 10 expression is correlated with thrombospondin expression and decreased vascular involvement in colon cancer

Tsutomu Kawakami, Tetsuji Tokunaga, Hiroyuki Hatanaka et al. · International Journal of Oncology · 2001 · 24 citations

T-regulatory Cell, Immunology, Pathology +16