Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study

Hin Chu, Jasper Fuk‐Woo Chan, Terrence Tsz‐Tai Yuen, +25

The Lancet Microbe

Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters

Shuofeng Yuan, Zi‐Wei Ye, Ronghui Liang, +27

Science

VaccinationContact TransmissionNew VariantPathogenesisViral Pathogenesis +11

Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs

Jasper Fuk‐Woo Chan, Cyril Chik‐Yan Yip, Jessica Oi‐Ling Tsang, +15

Emerging Microbes & Infections

Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor

Jasper Fuk‐Woo Chan, Kenn Ka‐Heng Chik, Shuofeng Yuan, +12

Antiviral Research

PathogenesisAntiviral Drug DevelopmentAntiviral ResponseAntiviral TherapyVirology +6

Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons

Jasper Fuk‐Woo Chan, Jinxia Zhang, Chris Chung‐Sing Chan, +15

EBioMedicine

Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system

Shuofeng Yuan, Jasper Fuk‐Woo Chan, Kenn Ka-Hang Chik, +13

Pharmacological Research

Drug SafetyFda-approved Drugs BexarotenePreclinical Drug EvaluationMedicineAntiviral Therapy +6

SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters

Wei Qiao, Hui En Lau, Huizhi Xie, +12

Nature Communications

Viral PathogenesisImmunologyPathologyImmune SystemOsteoporosis +15

Targeting papain-like protease for broad-spectrum coronavirus inhibition

Shuofeng Yuan, Xiaopan Gao, Kaiming Tang, +20

Protein & Cell

Improved detection of Zika virus <scp>RNA</scp> in human and animal specimens by a novel, highly sensitive and specific real‐time RT‐PCR assay targeting the 5′‐untranslated region of Zika virus

Jasper Fuk‐Woo Chan, Cyril Chik‐Yan Yip, Kah‐Meng Tee, +13

Tropical Medicine & International Health

Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells

Bingpeng Yan, Zijiao Zou, Hin Chu, +11

International Journal of Molecular Sciences

Molecular VirologyViral PersistenceFatty AcidsVirus InfectionPathogenesis +11