Kenn Ka‐Heng Chik

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study

Hin Chu, Jasper Fuk‐Woo Chan, Terrence Tsz‐Tai Yuen et al. · The Lancet Microbe · 2020 · 836 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters

Shuofeng Yuan, Zi‐Wei Ye, Ronghui Liang et al. · Science · 2022 · 222 citations

Veterinary Medicine, Immunology, Infectious Diseases +17

Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters

Shuofeng Yuan, Runming Wang, Jasper Fuk‐Woo Chan et al. · Nature Microbiology · 2020 · 198 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +12

Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs

Jasper Fuk‐Woo Chan, Cyril Chik‐Yan Yip, Jessica Oi‐Ling Tsang et al. · Emerging Microbes & Infections · 2016 · 186 citations · Full text

Veterinary Medicine, Infectious Diseases, Microbiology +17

Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo

Shuofeng Yuan, Jasper Fuk‐Woo Chan, Helena den-Haan et al. · Antiviral Research · 2017 · 134 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +15