Zhongqi Shen

2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of <i>N</i> -(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent <i>pan</i> -Src Kinase Inhibitor

Jagabandhu Das, Ping Chen, Derek Norris et al. · Journal of Medicinal Chemistry · 2006 · 393 citations · Full text

A new facile method for the synthesis of 1-arylimidazole-5-carboxylates

Bang‐Chi Chen, Mark S. Bednarz, Joseph E. Sundeen et al. · Tetrahedron Letters · 2000 · 178 citations

Engineering, Organic Chemistry, Synthesis Method +3

Molecular design, synthesis, and structure–Activity relationships leading to the potent and selective p56lck inhibitor BMS-243117

Jagabandhu Das, James C. Lin, Robert V. Moquin et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 58 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +14

Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck

John Wityak, Jagabandhu Das, Robert V. Moquin et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 56 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +11

Acridone-Based Inhibitors of Inosine 5‘-Monophosphate Dehydrogenase:  Discovery and SAR Leading to the Identification of <i>N</i>-(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)

Scott H. Watterson, Ping Chen, Yufen Zhao et al. · Journal of Medicinal Chemistry · 2007 · 49 citations · Full text

Sar Leading, Pharmaceutical Science, Inosine 5 +17