Derek J. Leishman

Structural Determinants of HERG Channel Block by Clofilium and Ibutilide

Matthew Perry, Marcel J. de Groot, R. M. Helliwell et al. · Molecular Pharmacology · 2004 · 157 citations

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

Hugo M. Vargas, Alan Bass, Alexander Breidenbach et al. · Journal of Pharmacological and Toxicological Methods · 2008 · 124 citations

Cardiovascular Translational Research, Cardiovascular Disease, Scientific Review +7

Towards a drug concentration effect relationship for QT prolongation and torsades de pointes.

Rob Webster, Derek J. Leishman, Don K. Walker · PubMed · 2002 · 116 citations

Pharmacotherapy, Experimental Pharmacology, Molecular Pharmacology +17

Mechanism of hERG K⁺channel blockade by the fluoroquinolone antibiotic moxifloxacin

Ari Alexandrou, Rona S. Duncan, A SULLIVAN et al. · British Journal of Pharmacology · 2006 · 114 citations · Full text

General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA <i>In Silico</i> Strategy

Zhihua Li, Gary R. Mirams, Takashi Yoshinaga et al. · Clinical Pharmacology & Therapeutics · 2019 · 106 citations · Full text