Rona S. Duncan

The N588K-HERG K+ channel mutation in the ‘short QT syndrome’: Mechanism of gain-in-function determined at 37 °C

Mark J. McPate, Rona S. Duncan, James T. Milnes et al. · Biochemical and Biophysical Research Communications · 2005 · 127 citations

Life Sciences, Genetics, Molecular Genetics +14

Mechanism of hERG K⁺channel blockade by the fluoroquinolone antibiotic moxifloxacin

Ari Alexandrou, Rona S. Duncan, Jules C. Hancox et al. · British Journal of Pharmacology · 2006 · 114 citations · Full text

Natural Sciences, Medicinal Chemistry, Pharmacology +17

Disopyramide is an effective inhibitor of mutant HERG K+ channels involved in variant 1 short QT syndrome

Mark J. McPate, Rona S. Duncan, Harry J. Witchel et al. · Journal of Molecular and Cellular Cardiology · 2006 · 92 citations

Natural Sciences, Genetics, Pharmacotherapy +16

Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin

Rona S. Duncan, Mark J. McPate, John Ridley et al. · Biochemical Pharmacology · 2007 · 57 citations · Full text

Medicine, Cardiology, Pharmacology +17

Erythromycin block of the HERG K+ channel: Accessibility to F656 and Y652

Rona S. Duncan, John Ridley, Christopher E. Dempsey et al. · Biochemical and Biophysical Research Communications · 2006 · 42 citations

Natural Sciences, Biophysics, Pharmacology +14