Mark J. McPate - Concepedia

Author

Mark J. McPate

University of Bristol

Also Known As

M J McPate, M McPate, M.J. McPate, MARK J. MCPATE, Mark J McPate, Mark J. McPate, Mark McPate, McPate, Mark

Publications

Citations

H-Index

Concepts

All Affiliations

University of Bristol University of Manchester Novartis (United Kingdom)Novartis Institutes for BioMedical Research Novartis (Switzerland)

About

Mark J. McPate is an author at University of Bristol specializing in medicine, signal transduction, and cell signaling.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	402
2	Cell Biology	2	2	128
3	Natural Sciences	1	1	20
4	Public Health	1	1	14
5	Biochemistry	1	1	20

Mark J. McPate

Publications

729

Citations

H-Index

Page 1

	Year	Citations
The N588K-HERG K+ channel mutation in the ‘short QT syndrome’: Mechanism of gain-in-function determined at 37 °C Mark J. McPate, Rona S. Duncan, James T. Milnes, Biochemical and Biophysical Research Communications ChannelopathiesSignal TransductionMendelian DisorderGenetic DisorderGenetics	2005	127
Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation Cheryl Carson, Pichai Raman, Jennifer Tullai, PLoS ONE Trpc4/c5 Cation ChannelsTrpc4 ChannelCancer BiologyCellular PhysiologyTumor Biology	2015	108
Pharmacology of the short QT syndrome N588K‐hERG K<sup>+</sup> channel mutation: differential impact on selected class I and class III antiarrhythmic drugs Mark J. McPate, R S Duncan, JC Hancox, British Journal of Pharmacology	2008	102
Disopyramide is an effective inhibitor of mutant HERG K+ channels involved in variant 1 short QT syndrome Mark J. McPate, Rona S. Duncan, Harry J. Witchel, Journal of Molecular and Cellular Cardiology Molecular PharmacologyChannelopathiesSignal TransductionShort Qt SyndromeMedicine	2006	91
Increased Vulnerability of Human Ventricle to Re-entrant Excitation in hERG-linked Variant 1 Short QT Syndrome Ismail Adeniran, Mark J. McPate, Harry J. Witchel, PLoS Computational Biology	2011	68
Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin Rona S. Duncan, Mark J. McPate, John Ridley, Biochemical Pharmacology	2007	57
Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome Aziza El Harchi, Mark J. McPate, Yihong Zhang, Journal of Molecular and Cellular Cardiology	2009	40
Inhibition of the HERG K<sup>+</sup>channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656 John Ridley, James T. Milnes, Rona S. Duncan, FEBS Letters	2006	31
Acidosis Impairs the Protective Role of hERG K<sup>+</sup> Channels Against Premature Stimulation CHUN YUN DU, Ismail Adeniran, Hongwei Cheng, Journal of Cardiovascular Electrophysiology	2010	29
Action potential clamp and mefloquine sensitivity of recombinant 'I KS' channels incorporating the V307L KCNQ1 mutation. Aziza El Harchi, Mark J. McPate, Yihong Zhang, PubMed Cardiac MuscleSudden DeathMolecular BiologyAccelerated Ventricular RepolarisationCellular Physiology	2010	22

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