Hugo M. Vargas

Torcetrapib‐induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone

M J Forrest, Daniel M. Bloomfield, Richard J. Briscoe et al. · British Journal of Pharmacology · 2008 · 283 citations · Full text

Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine.

Gina M. Bores, Francis P. Huger, Wayne W. Petko et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 247 citations

Design, Synthesis, and Evaluation of a Novel 4-Aminomethyl-4-fluoropiperidine as a T-Type Ca²⁺Channel Antagonist

William D. Shipe, James C. Barrow, Zhi-Qiang Yang et al. · Journal of Medicinal Chemistry · 2008 · 131 citations · Full text

Medicinal Chemistry, Selective Antagonist, Medicine +12

Current challenges in the evaluation of cardiac safety during drug development: Translational medicine meets the Critical Path Initiative

Jonathan P. Piccini, David J. Whellan, Brian R. Berridge et al. · American Heart Journal · 2009 · 125 citations

Drug Safety, Translational Medicine, Heart Failure +12

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

Hugo M. Vargas, Alan Bass, Alexander Breidenbach et al. · Journal of Pharmacological and Toxicological Methods · 2008 · 124 citations

Cardiovascular Translational Research, Cardiovascular Disease, Scientific Review +7