Concepedia

Marcel J. de Groot

MJ

Statistics

Publications

30

Citations

2.5K

H-Index

24

Active since

1990

Affiliations

Pfizer (United Kingdom)(Current)

Vrije Universiteit Amsterdam

Pfizer (United States)

Institute of Medicinal Plant Development

Centre for Human Drug Research

Marcel J. de Groot is an author at Pfizer (United Kingdom) specializing in pharmacology, cytochrome p450 enzymes, and medicine.

Publications per year

1990–2022

30

Publications

30

A Quantum Chemical Explanation of the Antioxidant Activity of Flavonoids

S.A.B.E. van Acker, Marcel J. de Groot, Dirk‐Jan van den Berg et al. · Chemical Research in Toxicology · 1996 · 404 citations

, , +14

Pharmacophore and three-dimensional quantitative structure activity relationship methods for modeling cytochrome p450 active sites.

Sean Ekins, Marcel J. de Groot, Jeffrey P. Jones · PubMed · 2001 · 202 citations

, , +17

Novel Approach To Predicting P450-Mediated Drug Metabolism:  Development of a Combined Protein and Pharmacophore Model for CYP2D6

Marcel J. de Groot, Mark J. Ackland, Valerie A. Horne et al. · Journal of Medicinal Chemistry · 1999 · 160 citations

, , +17

Structural Determinants of HERG Channel Block by Clofilium and Ibutilide

Matthew Perry, Marcel J. de Groot, R. M. Helliwell et al. · Molecular Pharmacology · 2004 · 159 citations

, , +17

Quantum Mechanics/Molecular Mechanics Modeling of Regioselectivity of Drug Metabolism in Cytochrome P450 2C9

Richard Lonsdale, Kerensa T. Houghton, Jolanta Żurek et al. · Journal of the American Chemical Society · 2013 · 150 citations · Full text

, , +17

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