Valerie A. Horne

Novel Approach To Predicting P450-Mediated Drug Metabolism:  Development of a Combined Protein and Pharmacophore Model for CYP2D6

Marcel J. de Groot, Mark J. Ackland, Valerie A. Horne et al. · Journal of Medicinal Chemistry · 1999 · 160 citations

Medicine, Biochemistry, Pharmacology +17

A Novel Approach to Predicting P450 Mediated Drug Metabolism. CYP2D6 Catalyzed N-Dealkylation Reactions and Qualitative Metabolite Predictions Using a Combined Protein and Pharmacophore Model for CYP2D6

Marcel J. de Groot, Mark J. Ackland, Valerie A. Horne et al. · Journal of Medicinal Chemistry · 1999 · 128 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Selective Urokinase-Type Plasminogen Activator Inhibitors. 4. 1-(7-Sulfonamidoisoquinolinyl)guanidines

Paul V. Fish, Chris Barber, David G. Brown et al. · Journal of Medicinal Chemistry · 2007 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines

Chris Barber, Roger P. Dickinson, Valerie A. Horne · Bioorganic & Medicinal Chemistry Letters · 2002 · 31 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +3

2,4-Diaminopyridine δ-opioid receptor agonists and their associated hERG pharmacology

Dafydd R. Owen, Margarita Rodriguez‐Lens, Martin Corless et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 10 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10