David O. Toft

HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

Jeffrey J. Kovacs, Patrick J. Murphy, Stéphanie Gaillard et al. · Molecular Cell · 2005 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

James P. Grenert, W. Patrick Sullivan, Patrick Fadden et al. · Journal of Biological Chemistry · 1997 · 570 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Bradley T. Scroggins, Kenneth Robzyk, Dongxia Wang et al. · Molecular Cell · 2007 · 411 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin

Theodor W. Schulte, Shiro Akinaga, Shiro Soga et al. · Cell Stress and Chaperones · 1998 · 403 citations · Full text

Medicine, Pharmacology, Molecular Pharmacology +3

The hsp90-related Protein TRAP1 Is a Mitochondrial Protein with Distinct Functional Properties

Sara J. Felts, Barbara Owen, Phuongmai Nguyen et al. · Journal of Biological Chemistry · 2000 · 373 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +5