David O. Toft

HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

Jeffrey J. Kovacs, Patrick J. Murphy, Stéphanie Gaillard et al. · Molecular Cell · 2005 · 1.1K citations · Full text

Signal Transduction, Molecular Regulation, Natural Sciences +8

The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

James P. Grenert, W. Patrick Sullivan, Patrick Fadden et al. · Journal of Biological Chemistry · 1997 · 568 citations · Full text

Crystal Structure, Protein Assembly, Atp/adp Switch Domain +18

An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Bradley T. Scroggins, Kenneth Robzyk, Dongxia Wang et al. · Molecular Cell · 2007 · 408 citations · Full text

Acetylation Site, Middle Domain, Protein Function +9

Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin

Theodor W. Schulte, Shiro Akinaga, Shiro Soga et al. · Cell Stress and Chaperones · 1998 · 399 citations · Full text

Medicine, N-terminal Domain, Molecular Biology +5

Molecular Chaperone Machines: Chaperone Activities of the Cyclophilin Cyp-40 and the Steroid Aporeceptor-Associated Protein p23

Brian Freeman, David O. Toft, Richard I. Morimoto · Science · 1996 · 370 citations

Chaperone Activities, Protein Assembly, Molecular Biology +16