Bradley T. Scroggins

Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness

Brenda K. Eustace, Takashi Sakurai, Jean K. Stewart et al. · Nature Cell Biology · 2004 · 587 citations

Proteomic Technology, Tumor Biology, Signaling Pathway +14

An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Bradley T. Scroggins, Kenneth Robzyk, Dongxia Wang et al. · Molecular Cell · 2007 · 408 citations · Full text

Acetylation Site, Middle Domain, Protein Function +9

Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90

Byoung Heon Kang, Janet Plescia, Ho Young Song et al. · Journal of Clinical Investigation · 2009 · 239 citations · Full text

Chemoprevention Strategy, Cancer Biology, Combinatorial Drug Design +24

Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species

Sunil Sudarshan, Carole Sourbier, Hye-Sik Kong et al. · Molecular and Cellular Biology · 2009 · 220 citations · Full text

Metabolic Remodeling, Reactive Oxygen Species, Redox Biology +22

Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function

Mehdi Mollapour, Shinji Tsutsumi, Alison C. Donnelly et al. · Molecular Cell · 2010 · 191 citations · Full text

Protein Function, Signal Transduction, Chaperone Function +11