Carole Sourbier

Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis

Soichiro Yoshida, Shinji Tsutsumi, Guillaume Mühlebach et al. · Proceedings of the National Academy of Sciences · 2013 · 300 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species

Sunil Sudarshan, Carole Sourbier, Hye-Sik Kong et al. · Molecular and Cellular Biology · 2009 · 221 citations · Full text

Medicine, Biochemistry, Oncology +17

The Glycolytic Shift in Fumarate-Hydratase-Deficient Kidney Cancer Lowers AMPK Levels, Increases Anabolic Propensities and Lowers Cellular Iron Levels

Wing‐Hang Tong, Carole Sourbier, Gennady Kovtunovych et al. · Cancer Cell · 2011 · 214 citations · Full text

Medicine, Cancer Biology, Oncology +16

Metformin Targets Mitochondrial Glycerophosphate Dehydrogenase to Control Rate of Oxidative Phosphorylation and Growth of Thyroid Cancer <i>In Vitro</i> and <i>In Vivo</i>

Shilpa Thakur, Brianna Daley, Kelli Gaskins et al. · Clinical Cancer Research · 2018 · 161 citations · Full text

Life Sciences, Oncology, Pharmacology +17

The Phosphoinositide 3-Kinase/Akt Pathway: A New Target in Human Renal Cell Carcinoma Therapy

Carole Sourbier, Véronique Lindner, Hervé Lang et al. · Cancer Research · 2006 · 153 citations · Full text

Medicine, Oncology, Pharmacology +17