Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly

Lee D. Fader, Richard C. Bethell, Pierre Bonneau, +22

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryHeterocyclicBiochemistryNatural Sciences +6

Compound Aggregation in Drug Discovery: Implementing a Practical NMR Assay for Medicinal Chemists

Steven R. LaPlante, Rebekah Carson, James Gillard, +7

Journal of Medicinal Chemistry

Practical Nmr AssayPharmaceutical ScienceCompound AggregationChemistryPharmaceutical Chemistry +22

Peptidomimetic Inhibitors of the Human Cytomegalovirus Protease

William Ogilvie, Murray D. Bailey, Marc‐André Poupart, +22

Journal of Medicinal Chemistry

Bioorganic ChemistrySelective SubstitutionImmunologyAntiviral DrugImmunotherapy +15

Phosphatidylinositol 4-Kinase III Beta Is Essential for Replication of Human Rhinovirus and Its Inhibition Causes a Lethal Phenotype <i>In Vivo</i>

Catherine Spickler, Julie Lippens, Marie-Kristine Laberge, +11

Antimicrobial Agents and Chemotherapy

β-Lactam Derivatives as Inhibitors of Human Cytomegalovirus Protease

Christiane Yoakim, William W. Ogilvie, Dale R. Cameron, +7

Journal of Medicinal Chemistry

Bioorganic ChemistryImmunologyAntiviral DrugDrug ResistanceMedicinal Chemistry +14

Discovery of the first series of inhibitors of human papillomavirus type 11: inhibition of the assembly of the E1–E2–Origin DNA complex

Christiane Yoakim, William W. Ogilvie, Nathalie Goudreau, +6

Bioorganic & Medicinal Chemistry Letters

Virus StructureFirst SeriesMolecular BiologyVirologyE1–e2–origin Dna Complex +5

Multiple modes of insecticidal action of three classes of polyacetylene derivatives from Rudbeckia hirta

Gabriel Guillet, Bernard J. R. Philogène, Jeff A. O’Meara, +2

Phytochemistry

BiologyBioorganic ChemistryNatural SciencesEntomologyOrganic Chemistry +5

Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors

Jeff A. O’Meara, Araz Jakalian, Steven R. LaPlante, +9

Bioorganic & Medicinal Chemistry Letters

Scaffold HoppingBiochemistryProtein FoldingRational DesignNatural Sciences +10

Enantioselective Synthesis of β-Dibenzylamino Alcohols via a Dynamic Kinetic Resolution of α-Halo Acids

Jeff A. O’Meara, Nizar Gardee, Manfred Jung, +2

The Journal of Organic Chemistry

EngineeringBiochemistryNatural SciencesDiversity-oriented SynthesisAltmetric Attention Score +11

Evidence of a Conformational Change in the Human Cytomegalovirus Protease upon Binding of Peptidyl-Activated Carbonyl Inhibitors

Pierre Bonneau, Chantal Grand‐Maître, Daniel J. Greenwood, +6

Biochemistry