Jürgen Groet

The importance of understanding individual differences in Down syndrome

Annette Karmiloff‐Smith, Tamara Al‐Janabi, Hana D’Souza et al. · F1000Research · 2016 · 207 citations · Full text

Life Sciences, Genetics, Neuroscience +15

Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder

Jürgen Groet, Suzanne McElwaine, Mônica Glória Neumann Spínelli et al. · The Lancet · 2003 · 167 citations

Life Sciences, Genetics, Molecular Genetics +11

DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome

Claudia Canzonetta, Claire Mulligan, Samuel Deutsch et al. · The American Journal of Human Genetics · 2008 · 158 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

Ivan Alić, Pollyanna Goh, Aoife Murray et al. · Molecular Psychiatry · 2020 · 123 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration

Aoife Murray, Audrey Letourneau, Claudia Canzonetta et al. · Stem Cells · 2015 · 82 citations · Full text

Life Sciences, Cell Biology, Genetics +17