Common Regulatory Variation Impacts Gene Expression in a Cell Type–Dependent Manner

Antigone S. Dimas, Samuel Deutsch, Barbara E. Stranger, +12

Science

Phenotypic VariationGeneticsGene Regulatory NetworkGene Expression ProfilingCell Type-specific Eqtls +19

Genome-Wide Associations of Gene Expression Variation in Humans

Barbara E. Stranger, Matthew S. Forrest, Andrew G. Clark, +8

PLoS Genetics

Quantitative VariationGenome-wide Association StudyHapmap Cell LinesHaplotype DeterminationFunctional Genomics +13

Genetic Structure of Europeans: A View from the North–East

Mari Nelis, Tōnu Esko, Reedik Mägi, +40

PLoS ONE

Genotype-phenotype AssociationMolecular EcologyHuman VariationMedicineGenetics +13

Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome

Weibing Shi, Christina D. Moon, Sinead C. Leahy, +20

Genome Research

Human microRNA-155 on Chromosome 21 Differentially Interacts with Its Polymorphic Target in the AGTR1 3′ Untranslated Region: A Mechanism for Functional Single-Nucleotide Polymorphisms Related to Phenotypes

Praveen Sethupathy, Christelle Borel, Maryline Gagnebin, +5

The American Journal of Human Genetics

Polymorphic TargetEngineeringHuman Microrna-155MedicineGenetics +9

Domains of genome-wide gene expression dysregulation in Down’s syndrome

Audrey Letourneau, Federico Santoni, Ximena Bonilla, +25

Nature

Down SyndromeGenetic DisorderGeneticsDisease Gene IdentificationDown ’ +2

Numerous potentially functional but non-genic conserved sequences on human chromosome 21

Emmanouil T. Dermitzakis, Alexandre Reymond, Robert Lyle, +8

Nature

Polymorphisms in the Low-Density Lipoprotein Receptor–Related Protein 5 (LRP5) Gene Are Associated with Variation in Vertebral Bone Mass, Vertebral Bone Size, and Stature in Whites

Serge Ferrari, Samuel Deutsch, Urmila Choudhury, +5

The American Journal of Human Genetics

Vertebral Bone SizeGene Are AssociatedGeneticsGenetic EpidemiologyHuman Polymorphism +7

Gene Expression From the Aneuploid Chromosome in a Trisomy Mouse Model of Down Syndrome

Robert Lyle, Corinne Gehrig, Charlotte Neergaard-Henrichsen, +2

Genome Research

Natural Gene-Expression Variation in Down Syndrome Modulates the Outcome of Gene-Dosage Imbalance

Paola Prandini, Samuel Deutsch, Robert Lyle, +11

The American Journal of Human Genetics

Down SyndromeGenetic AnalysisNatural Gene-expression VariationGenetic DisorderGenetics +6