PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Vamsi K. Mootha, Cecilia M. Lindgren, Karl‐Fredrik Eriksson, +18

Nature Genetics

Metabolic SyndromeHuman DiabetesBiochemistryDiabetesPgc-1α-responsive Genes +8

Multiple regions within 8q24 independently affect risk for prostate cancer

Christopher A. Haiman, Nick Patterson, Matthew L. Freedman, +23

Nature Genetics

UrologyCancer RiskCancer EpidemiologyMedicineEpidemiology Of Cancer +4

MYH9 is associated with nondiabetic end-stage renal disease in African Americans

W.H. Linda Kao, Michael J. Klag, Lucy A. Meoni, +28

Nature Genetics

GlomerulonephritisUrologyRenal DiseaseRenal FunctionKidney Research +10

A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer

Justin Lamb, Sridhar Ramaswamy, Heide L. Ford, +7

Cell

MedicineCancer GenomicsHuman CancerTumor SuppressorCancer Genetics +6

Extreme Polygenicity of Complex Traits Is Explained by Negative Selection

Luke J. O’Connor, Armin Schoech, Farhad Hormozdiari, +3

The American Journal of Human Genetics

BiologyGenotype-phenotype AssociationMedicineGeneticsEvolutionary Biology +8

Prospective functional classification of all possible missense variants in PPARG

Amit R. Majithia, Ben Tsuda, Maura Agostini, +20

Nature Genetics

Genetic AnalysisAllelic VariantGenotype-phenotype AssociationProspective Functional ClassificationGenetics +7

An Atlas of Genetic Correlations across Human Diseases and Traits

Brendan Bulik‐Sullivan, Hilary K. Finucane, Verneri Anttila, +9

GeneticsGenetic CorrelationsGenetic EpidemiologyGenome-wide Association StudiesClinical Genetics +15

Liability threshold modeling of case–control status and family history of disease increases association power

Margaux L.A. Hujoel, Steven Gazal, Po‐Ru Loh, +2

Nature Genetics

Family MedicineFamily HealthDisease Risk AssessmentGenetic EpidemiologyHealth Insurance +10

Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies

Noah Zaitlen, Sara Lindström, Bogdan Paşaniuc, +43

PLoS Genetics

Admixture Mapping of 15,280 African Americans Identifies Obesity Susceptibility Loci on Chromosomes 5 and X

Ching‐Yu Cheng, W.H. Linda Kao, Nick Patterson, +34

PLoS Genetics

GeneticsGenetic EpidemiologyAnthropometric IndicatorAfrican AmericansChromosome X +14