Sridhar Ramaswamy

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

Wanjuan Yang, Jorge Soares, Patricia Greninger et al. · Nucleic Acids Research · 2012 · 4.2K citations · Full text

Therapeutic Biomarker Discovery, Drug Target, Engineering +21

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

David A. Barbie, Pablo Tamayo, Jesse S. Boehm et al. · Nature · 2009 · 4.1K citations · Full text

Systems Biology, Oncogenic Agent, Medicine +4

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

Jing Yang, Sendurai A. Mani, Joana Liu Donaher et al. · Cell · 2004 · 3.8K citations · Full text

Developmental Biology, Essential Role, Tumor Heterogeneity +7

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

Sreenath V. Sharma, Diana Lee, Bihua Li et al. · Cell · 2010 · 2.7K citations · Full text

Chromatin, Chromatin Remodeling, Medicine +6

Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn et al. · Nature · 2012 · 2.5K citations · Full text

Systematic Identification, Genomic Markers, Engineering +12