The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao, +12

Cell

Regenerative MedicineEpithelial-mesenchymal TransitionDevelopmental BiologyMedicineAdult Stem Cell +7

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

Jing Yang, Sendurai A. Mani, Joana Liu Donaher, +7

Cell

Developmental BiologyEssential RoleTumor HeterogeneityMedicineMorphogenesis +5

Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways

Tamer T. Önder, Piyush B. Gupta, Sendurai A. Mani, +3

Cancer Research

Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis

Jeff H. Tsai, Joana Liu Donaher, Danielle Murphy, +2

Cancer Cell

Epithelial-mesenchymal TransitionMedicineBiological MicroenvironmentsPathologyEpithelial-mesenchymal Interactions +8

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

Joseph H. Taube, Jason I. Herschkowitz, Kakajan Komurov, +13

Proceedings of the National Academy of Sciences

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

Spencer C. Wei, Laurent Fattet, Jeff H. Tsai, +8

Nature Cell Biology

MechanobiologyTumor BiologyTumour MetastasisMedicineCancer Cell Biology +11

CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

Rhonda L. Brown, Lauren M. Reinke, Marin S. Damerow, +4

Journal of Clinical Investigation

PathologyCancer BiologyCd44 ExpressionTumor BiologyBreast Cancer Progression +14

Mesenchyme Forkhead 1 ( <i>FOXC2</i> ) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

Sendurai A. Mani, Jing Yang, Mary W. Brooks, +7

Proceedings of the National Academy of Sciences

Breast OncologyKey RolePathologyCancer BiologyGene Expression Profiling +15

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

Mark A. Eckert, Thinzar M. Lwin, Andrew Chang, +4

Cancer Cell

MedicineTumor SuppressorCancer BiologyCell BiologyCancer Research +2

Snail2 is an Essential Mediator of Twist1-Induced Epithelial Mesenchymal Transition and Metastasis

Esmeralda Casas-Silva, Jihoon Kim, Andrés Bendesky, +3

Cancer Research