Sreenath V. Sharma

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

Sreenath V. Sharma, Diana Lee, Bihua Li et al. · Cell · 2010 · 2.7K citations · Full text

Chromatin, Chromatin Remodeling, Medicine +6

Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn et al. · Nature · 2012 · 2.5K citations · Full text

Systematic Identification, Genomic Markers, Engineering +12

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

Eunice L. Kwak, Raffaella Sordella, Daphne W. Bell et al. · Proceedings of the National Academy of Sciences · 2005 · 951 citations · Full text

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR

Daphne W. Bell, Ira Gore, Ross A. Okimoto et al. · Nature Genetics · 2005 · 528 citations

Tumor Biology, Somatic Variant, Medicine +9

Elevated CRAF as a Potential Mechanism of Acquired Resistance to BRAF Inhibition in Melanoma

Clara Montagut, Sreenath V. Sharma, Toshi Shioda et al. · Cancer Research · 2008 · 502 citations · Full text