G. Ralph

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

G. Ralph, Pippa A. Radcliffe, Denise M. Day et al. · Nature Medicine · 2005 · 499 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Rnai Protects +8

Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial

Stéphane Palfi, Jean Marc Gurruchaga, G. Ralph et al. · The Lancet · 2014 · 432 citations

Gene Therapies, Neurodegenerative Diseases, Dose Escalation +11

Surface Expression of AMPA Receptors in Hippocampal Neurons Is Regulated by an NSF-Dependent Mechanism

Jacques Noël, G. Ralph, Lisa Pickard et al. · Neuron · 1999 · 302 citations · Full text

Nsf-dependent Mechanism, Molecular Physiology, Neurophysiology +12

Removal of AMPA Receptors (AMPARs) from Synapses Is Preceded by Transient Endocytosis of Extrasynaptic AMPARs

Michael C. Ashby, Sarah A. De La Rue, G. Ralph et al. · Journal of Neuroscience · 2004 · 241 citations · Full text

Synaptic Transmission, Neurotransmitter, Neurotransmission +18

Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy

Mimoun Azzouz, Thanh T. Le, G. Ralph et al. · Journal of Clinical Investigation · 2004 · 198 citations · Full text

Immunology, Viral Pathogenesis, Sma Type 1 +16