Thanh T. Le

RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Kevin D. Foust, Xueyong Wang, Vicki L. McGovern et al. · Nature Biotechnology · 2010 · 685 citations · Full text

Knockout Mouse, Early Postnatal Delivery, Spinal Cord Injury +8

SMNΔ7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN

Thanh T. Le, Lan T. Pham, Matthew E.R. Butchbach et al. · Human Molecular Genetics · 2005 · 588 citations · Full text

SMN oligomerization defect correlates with spinal muscular atrophy severity

Christian L. Lorson, John Strasswimmer, Jun-Mei Yao et al. · Nature Genetics · 1998 · 494 citations

Spinal Cord Injury, Degenerative Disease, Neurology +5

Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy

Mimoun Azzouz, Thanh T. Le, G. Ralph et al. · Journal of Clinical Investigation · 2004 · 198 citations · Full text

Immunology, Viral Pathogenesis, Sma Type 1 +16

A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy

Umrao R. Monani, Matthew Pastore, Tatiana Gavrilina et al. · The Journal of Cell Biology · 2003 · 149 citations · Full text

A2g Missense Mutation, Smn Gene Modulates, Neurodegenerative Diseases +13