Mimoun Azzouz

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

G. Ralph, Pippa A. Radcliffe, Denise M. Day et al. · Nature Medicine · 2005 · 499 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Rnai Protects +8

Systemic Delivery of scAAV9 Expressing SMN Prolongs Survival in a Model of Spinal Muscular Atrophy

Chiara F. Valori, Ke Ning, Matthew Wyles et al. · Science Translational Medicine · 2010 · 280 citations

Regenerative Medicine, Amyotrophic Lateral Sclerosis, Spinal Cord Injury +12

Multicistronic Lentiviral Vector-Mediated Striatal Gene Transfer of Aromatic l-Amino Acid Decarboxylase, Tyrosine Hydroxylase, and GTP Cyclohydrolase I Induces Sustained Transgene Expression, Dopamine Production, and Functional Improvement in a Rat Model of Parkinson's Disease.

Mimoun Azzouz, Enca Martin‐Rendon, Robert D. Barber et al. · Journal of Neuroscience · 2002 · 218 citations · Full text

Neurodegenerative Diseases, Dopaminergic Neurons, Transgene Expression +15

Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy

Mimoun Azzouz, Thanh T. Le, G. Ralph et al. · Journal of Clinical Investigation · 2004 · 198 citations · Full text

Immunology, Viral Pathogenesis, Sma Type 1 +16

C9orf72 expansion disrupts ATM-mediated chromosomal break repair

Callum Walker, Saúl Herranz-Martín, Evangelia Karyka et al. · Nature Neuroscience · 2017 · 185 citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +4