Shoji Fukumoto

Identification of Benzoxazin-3-one Derivatives as Novel, Potent, and Selective Nonsteroidal Mineralocorticoid Receptor Antagonists

Tomoaki Hasui, Nobuyuki Matsunaga, Taiichi Ora et al. · Journal of Medicinal Chemistry · 2011 · 109 citations · Full text

Combinatorial Chemistry, Crystal Structure, Medicinal Chemistry +13

Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2)

Yasutomi Asano, Shuji Kitamura, Taiichi Ohra et al. · Bioorganic & Medicinal Chemistry · 2008 · 90 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +12

Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure

Tomohiro Okawa, Yoshio Aramaki, Mitsuo Yamamoto et al. · Journal of Medicinal Chemistry · 2017 · 58 citations · Full text

Novel, Non-acylguanidine-type Na⁺/H⁺ Exchanger Inhibitors:  Synthesis and Pharmacology of 5-Tetrahydroquinolinylidene Aminoguanidine Derivatives

Shoji Fukumoto, Eiko Imamiya, Keiji Kusumoto et al. · Journal of Medicinal Chemistry · 2002 · 46 citations · Full text

Discovery of an Orally Bioavailable, Brain-Penetrating, in Vivo Active Phosphodiesterase 2A Inhibitor Lead Series for the Treatment of Cognitive Disorders

Satoshi Mikami, Shigekazu Sasaki, Yasutomi Asano et al. · Journal of Medicinal Chemistry · 2017 · 41 citations · Full text

Drug Target, Lead Identification, Neurochemical Biomarkers +20