Yoshio Aramaki

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

Masanori Baba, Osamu Nishimura, Naoyuki Kanzaki et al. · Proceedings of the National Academy of Sciences · 1999 · 755 citations · Full text

Discovery of Novel, Potent, and Selective Small-Molecule CCR5 Antagonists as Anti-HIV-1 Agents:  Synthesis and Biological Evaluation of Anilide Derivatives with a Quaternary Ammonium Moiety

Mitsuru Shiraishi, Yoshio Aramaki, Masaki Seto et al. · Journal of Medicinal Chemistry · 2000 · 185 citations · Full text

Lead Compounds, Cho/ccr5 Cells, Lead Identification +19

Chemical characterization of spider toxin, JSTX and NSTX.

Yoshio Aramaki, Tadashi Yasuhara, Tsutomu Higashijima et al. · Proceedings of the Japan Academy Series B · 1986 · 111 citations · Full text

Microbial Toxin, Toxinology, Biochemistry +7

Orally active CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological activities of 1-benzazepine derivatives containing a sulfoxide moiety

Masaki Seto, Naoki Miyamoto, Katsuji Aikawa et al. · Bioorganic & Medicinal Chemistry · 2004 · 100 citations

Medicine, Active Ccr5 Antagonists, 1-Benzazepine Derivatives +7

Highly Potent and Orally Active CCR5 Antagonists as Anti-HIV-1 Agents:  Synthesis and Biological Activities of 1-Benzazocine Derivatives Containing a Sulfoxide Moiety

Masaki Seto, Katsuji Aikawa, Naoki Miyamoto et al. · Journal of Medicinal Chemistry · 2006 · 89 citations · Full text

Pharmaceutical Science, 1-Benzazocine Derivatives, Chemical Modification +18