Ralph J. DeBerardinis

Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

Taro Hitosugi, Lu Zhou, Shannon Elf et al. · Cancer Cell · 2012 · 418 citations · Full text

Biochemistry, Medicine, Tumor Growth +9

A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth

John C. Schell, Kristofor A. Olson, Lei Jiang et al. · Molecular Cell · 2014 · 374 citations · Full text

Systems Biology, Mitochondrial Pyruvate Carrier, Mitochondrial Function +10

Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth

Lingtao Jin, Dan Li, Gina N. Alesi et al. · Cancer Cell · 2015 · 353 citations · Full text

Reductive Stress, Redox Signaling, Biochemistry +12

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

Liping Jiang, Ling Xiao, Hidekazu Sugiura et al. · Oncogene · 2014 · 217 citations · Full text

Developmental Biology, Metabolic Reprogramming, Tgfβ1-induced Epithelial-to-mesenchymal Transition +6

Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis

Ruilong Liu, Xuelian Ren, Yae Eun Park et al. · Cell Metabolism · 2024 · 114 citations · Full text

Histone Lactylation, Chromatin, Signal Transduction +11