Concepedia

N H Sigal

NH

59

Publications

6.1K

Citations

34

H-Index

1972

Active since

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Hospital for Sick Children

University of Pennsylvania

Princeton University

University of Toronto

N H Sigal is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, immunology, and cell biology.

ORCID

Top concepts

Publications per year

1972–2005

59

Publications

59

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

John J. Siekierka, Shirley H.Y. Hung, Martin Poe et al. · Nature · 1989 · 1K citations

, , +12

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin.

Francis J. Dumont, Mary Jo Staruch, Sam L. Koprak et al. · The Journal of Immunology · 1990 · 607 citations

A DNA-Unwinding Protein Isolated from <i>Escherichia coli:</i> Its Interaction with DNA and with DNA Polymerases

N H Sigal, Hajo Delius, Thomas B. Kornberg et al. · Proceedings of the National Academy of Sciences · 1972 · 358 citations · Full text

, , +20

The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.

Francis J. Dumont, Michael Melino, Mary Jo Staruch et al. · The Journal of Immunology · 1990 · 355 citations · Full text

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

N H Sigal, Francis J. Dumont, P. L. DURETTE et al. · The Journal of Experimental Medicine · 1991 · 249 citations · Full text

, , +18

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