V K Chaudhary

A rapid method of cloning functional variable-region antibody genes in Escherichia coli as single-chain immunotoxins.

V K Chaudhary, Janendra K. Batra, Maria Gallo et al. · Proceedings of the National Academy of Sciences · 1990 · 155 citations · Full text

Microbial Pathogens, Immunology, Molecular Biology +18

A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo

Yogendra Singh, V K Chaudhary, Stephen H. Leppla · Journal of Biological Chemistry · 1989 · 150 citations · Full text

Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma

RJ Kreitman, Pascal Bailon, V K Chaudhary et al. · Blood · 1994 · 139 citations · Full text

The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity

Yogendra Singh, Kurt R. Klimpel, Conrad P. Quinn et al. · Journal of Biological Chemistry · 1991 · 93 citations · Full text

Microbial Toxin, Anthrax Toxin, Protein Function +13

A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin.

V K Chaudhary, Maria Gallo, D J FitzGerald et al. · Proceedings of the National Academy of Sciences · 1990 · 79 citations

Toxinology, Anti-tac Variable Regions, Amino Acids +18