RJ Kreitman

Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma

RJ Kreitman, Pascal Bailon, V K Chaudhary et al. · Blood · 1994 · 139 citations · Full text

Life Sciences, Immunology, Oncology +15

Targeting of interleukin-13 receptor on human renal cell carcinoma cells by a recombinant chimeric protein composed of interleukin-13 and a truncated form of Pseudomonas exotoxin A (PE38QQR)

RK Puri, Pamela Leland, Obiri Ni et al. · Blood · 1996 · 118 citations · Full text

Life Sciences, Immunology, Oncology +17

Specific depletion of alloreactivity against haplotype mismatched related individuals by a recombinant immunotoxin: a new approach to graft-versus-host disease prophylaxis in haploidentical bone marrow transplantation.

DA. Mavroudis, Jiang Yz, Nancy F. Hensel et al. · PubMed · 1996 · 67 citations

Medicine, Hematology, Immunology +13

Prevention of graft-versus-host disease (GVHD) by elimination of recipient-reactive donor T cells with recombinant toxins that target the interleukin 2 (IL-2) receptor

DT Harris, Debbie Sakiestewa, Claire E. Lyons et al. · Bone Marrow Transplantation · 1999 · 62 citations

Life Sciences, Immunology, Pathobiology +17

Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia

RJ Kreitman, V K Chaudhary, RW Kozak et al. · Blood · 1992 · 55 citations · Full text

Medicine, Oncology, Pharmacology +15