Zhao‐Kui Wan

Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( <i>S</i> )-2,2-Difluorocyclopropyl)((1 <i>R</i> ,5 <i>S</i> )-3-(2-((1-methyl-1 <i>H</i> -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)

Andrew Fensome, Catherine M. Ambler, Eric P. Arnold et al. · Journal of Medicinal Chemistry · 2018 · 165 citations · Full text

Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors:  From the Active Site to the Second Phosphotyrosine Binding Site

Douglas Wilson, Zhao‐Kui Wan, Weixin Xu et al. · Journal of Medicinal Chemistry · 2007 · 156 citations · Full text

Proteinlipid Interaction, Drug Target, Molecular Biology +18

Asymmetric Ni(II)/Cr(II)-Mediated Coupling Reaction:  Catalytic Process

Hyeong-Wook Choi, Katsumasa Nakajima, Damtew Demeke et al. · Organic Letters · 2002 · 120 citations

Inorganic Chemistry, Chemical Engineering, Asymmetric Ni +11

The Scope and Mechanism of Phosphonium-Mediated S_NAr Reactions in Heterocyclic Amides and Ureas

Zhao‐Kui Wan, Sumrit Wacharasindhu, Christopher G. Levins et al. · The Journal of Organic Chemistry · 2007 · 111 citations

Heterocyclic, Biochemistry, Cyclic Amidines +10

Comparative performance evaluation and systematic screening of solvents in a range of Grignard reactions

Asha Kadam, My-Linh Nguyen, Michael E. Kopach et al. · Green Chemistry · 2013 · 108 citations · Full text

Solvent Extraction, Engineering, Green Chemistry +18