Cecilia Ström

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 525 citations

Tumor Biology, Dntp Pool, Mth1 Inhibition +8

Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate

Cecilia Ström, Fredrik Johansson, Mathias Uhlén et al. · Nucleic Acids Research · 2010 · 295 citations · Full text

Rna Processing, Genome Instability, Parp Inhibition +10

The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions

Manuel Luís Orta, Andreas Höglund, José Manuel Calderón‐Montaño et al. · Nucleic Acids Research · 2014 · 83 citations · Full text

XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair

Jason L. Parsons, Irina I. Dianova, David Finch et al. · DNA repair · 2010 · 66 citations

Genome Instability, Xrcc1 Phosphorylation, Cell Regulation +8

ATM‐mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double‐strand break repair

Hava Segal‐Raz, Gilad Mass, Keren Baranes‐Bachar et al. · EMBO Reports · 2011 · 59 citations · Full text

Genome Instability, Polynucleotide Kinase/phosphatase, Dna Damage +9