Steffen Lang

Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface

Inge Van Molle, Andreas Thomann, Dennis L. Buckley et al. · Chemistry & Biology · 2012 · 190 citations · Full text

Protein Function, Protein Assembly, Biochemistry +12

A three-stage biophysical screening cascade for fragment-based drug discovery

Ellene H. Mashalidis, P. Sledz, Steffen Lang et al. · Nature Protocols · 2013 · 132 citations

Fragment-based Drug Discovery, Hit Identification, Biochemistry +5

Using Ligand‐Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo‐Like Kinase 1

Yaw Sing Tan, P. Sledz, Steffen Lang et al. · Angewandte Chemie International Edition · 2012 · 81 citations · Full text

Proteinlipid Interaction, Drug Target, Engineering +19

Validation of Excised Bovine Nasal Mucosa as In Vitro Model to Study Drug Transport and Metabolic Pathways in Nasal Epithelium‡‡Data adopted from yet unpublished parts of the Ph.D. theses of Günter Ditzinger, Steffen Lang, and M. Christiane Schmidt

Mathias Schmidt, Daniel Simmen, Monika Hilbe et al. · Journal of Pharmaceutical Sciences · 2000 · 72 citations

Animal Physiology, Metabolic Pathways, Pharmacokinetic Modeling +9

From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo‐Like Kinase 1

P. Sledz, Christopher J. Stubbs, Steffen Lang et al. · Angewandte Chemie International Edition · 2011 · 70 citations · Full text

X-ray Crystallography, Engineering, Biomolecular Structure Prediction +16