Yaw Sing Tan

A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling

Henning S. G. Beckmann, Feilin Nie, Caroline E. Hagerman et al. · Nature Chemistry · 2013 · 135 citations

Combinatorial Chemistry, Diversity Oriented Synthesis, Engineering +12

Double Strain‐Promoted Macrocyclization for the Rapid Selection of Cell‐Active Stapled Peptides

Yu Heng Lau, Yuteng Wu, Maxim Rossmann et al. · Angewandte Chemie International Edition · 2015 · 128 citations · Full text

Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2

M. Janecek, Maxim Rossmann, Pooja Sharma et al. · Scientific Reports · 2016 · 91 citations · Full text

Diversity-oriented synthesis as a tool for identifying new modulators of mitosis

Brett M. Ibbeson, Luca Laraia, Esther Alza et al. · Nature Communications · 2014 · 82 citations

Diversity Oriented Synthesis, Cell Division, Medicine +13

Using Ligand‐Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo‐Like Kinase 1

Yaw Sing Tan, P. Sledz, Steffen Lang et al. · Angewandte Chemie International Edition · 2012 · 81 citations · Full text

Proteinlipid Interaction, Drug Target, Engineering +19