Youfeng Yang

Reductive carboxylation supports growth in tumour cells with defective mitochondria

Andrew R. Mullen, William W. Wheaton, Eunsook S. Jin et al. · Nature · 2011 · 1.3K citations · Full text

Biochemistry, Mitochondrial Function, Organelle Dynamic +7

The Amyotrophic Lateral Sclerosis 8 Protein VAPB Is Cleaved, Secreted, and Acts as a Ligand for Eph Receptors

Hiroshi Tsuda, Sung Min Han, Youfeng Yang et al. · Cell · 2008 · 238 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Signal Transduction +9

Succinate Dehydrogenase Kidney Cancer: An Aggressive Example of the Warburg Effect in Cancer

Christopher J. Ricketts, Brian Shuch, Cathy D. Vocke et al. · The Journal of Urology · 2012 · 237 citations · Full text

High Frequency of Somatic Frameshift BHD Gene Mutations in Birt-Hogg-Dubé–Associated Renal Tumors

Cathy D. Vocke, Youfeng Yang, Christian P. Pavlovich et al. · JNCI Journal of the National Cancer Institute · 2005 · 236 citations

Urology, Somatic Variant, Genitourinary Cancer +14

Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species

Sunil Sudarshan, Carole Sourbier, Hye-Sik Kong et al. · Molecular and Cellular Biology · 2009 · 220 citations · Full text

Metabolic Remodeling, Reactive Oxygen Species, Redox Biology +22