Vendula Hepnarová

Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease

Katarina Chalupova, Jan Korábečný, Manuela Bartolini et al. · European Journal of Medicinal Chemistry · 2019 · 106 citations · Full text

Neuropeptides, Drug Target, Biochemistry +11

The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease

Vendula Hepnarová, Jan Korábečný, Lenka Matoušková et al. · European Journal of Medicinal Chemistry · 2018 · 69 citations · Full text

Medicinal Chemistry, Alzheimer's Disease, Medicine +13

Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile

Kateřina Sobolová, Martina Hrabinová, Vendula Hepnarová et al. · European Journal of Medicinal Chemistry · 2020 · 33 citations · Full text

Medicinal Chemistry, Balanced Cholinesterase, Bioorganic Chemistry +12

(±)-<b>BIGI-3h</b>: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer’s Disease

Lhassane Ismaïli, Julie Monnin, Adeline Etiévant et al. · ACS Chemical Neuroscience · 2021 · 33 citations · Full text

Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors

Barbora Svobodová, Eva Mezeiová, Vendula Hepnarová et al. · Biomolecules · 2019 · 30 citations · Full text